Assessment of the anti-diabetic activity of deoxyspergualin in low-dose streptozotocin-induced diabetic mice.
نویسندگان
چکیده
In mice, five injections of sub-diabetogenic doses of streptozotocin (STZ) may cause diabetes mellitus associated with lymphocyte infiltration of pancreatic islets1*^. There is evidence implicating autoimmune processes in the pathogenesis of this experimental diabetes3 > 4). Significantly, the development of this diabetes was prevented by rabbit anti-mouse lymphocyte serum5). Since deoxyspergualin (NKT-01) has
منابع مشابه
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عنوان ژورنال:
- The Journal of antibiotics
دوره 41 1 شماره
صفحات -
تاریخ انتشار 1988